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Multi-layered devices that integrate microfluidic valves and on-chip peristaltic pumps have been used for more complex assays. First, the microfluidic research community has been actively engaged in developing and enhancing new processes and materials for the fabrication of LoCs, resulting in increased complexity and level of integration of chips. Research on LoC devices can be broadly categorized into two main areas. The requirement of smaller sample quantities, the increased accuracy and sensitivity of microfluidic operations, and the speed of performing once time-consuming protocols are some of the benefits realized by porting assays to microfluidic scale. Lab-on-a-Chip (LoC) devices have been used in a plethora of applications, ranging from basic bio-chemistry research, to chemical synthesis, genomics, proteomics, clinical diagnostics and drug discovery. Finally, we demonstrate our SPLoC on four diverse, real-world assays. We describe two key features of our high-level language compiler, and describe a novel variable-volume variable-ratio mixer. We describe the components necessary to realize the SPLoC, which include a high-level programming language, an abstract instruction set, a runtime and control system, and a microfluidic device.

In this paper, we develop a multi-purpose, software-programmableLab-on-a-Chip (SPLoC), where the user simply writes or downloads a program for each experiment. Similarly, minor modifications to an assay protocol re-incur the overheads of the design cycle. This prolonged cycle can take months to complete, increasing effort and cost and reducing productivity. Performing an experiment requires scientists or engineers to go through the time-consuming process of designing, fabricating, and testing a chip before conducting the actual experiment.

Current lab-on-a-chip (LoC) devices are assay-specific and are custom-built for each single experiment.

Hp solution center windows 10 download chip